Engineer ND, Riley JR, Seale JD, et al
Based on the k d (fractional turnover rate) value of 0.0133/day for the loss of intramuscular carnosine at the physiological steady state (Spelnikov and Harris 2019), the intramuscular concentrations of carnosine in women and men (17.5 and 21.3 mmol/kg dry weight, respectively), skeletal muscle mass (45% of BW), and its dry matter content (30%), it can be estimated that a 60-kg woman and a 70-kg man synthesizes 427 and 606 mg carnosine per day, respectively
Although the exact reason for such conflicting results is not clear, specific features of brain energy metabolism (Reference McKenna, Dienel, Sonnewald, Brady, Siegel and Albers48) , concurrent supplementation with other antioxidants or probable technical issues may be involved in producing these results
Make sure you keep up with all of your appointments and blood tests so your provider can monitor your treatment and properly adjust your hydroxocobalamin dose