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Our premise is that under physiological conditions, mitogen-induced signaling that propagates down the pathway into the cell cycle is strong, but the bursts are of short duration (Figure 1C)

Like if you have an elbow injury, they'll put it into the muscle right above the elbow or subcutaneously right above the elbow

Calcipotriol worked faster in the first four to eight weeks, but by week 12 the two treatments produced similar reductions in PASI and the B12 cream was better tolerated (Stucker 2001)

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