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Butyrate essentially fuels colon cells and is crucial for the neuroimmunoendocrine system, promoting gut health through its anti-inflammatory properties and strengthening the intestinal barrier [43]

While evidence from genetic studies, meta-analyses, and specific cardiovascular outcome trials (CVOTs) supports an association between certain GLP-1RAs and reduced AF risk, conflicting data exist regarding drug-specific effects, underscoring the need for further mechanistic and outcome research

In fact, the possibility of using glutathione for therapeutic purposes other than oxidative stress and further exploring the mechanisms by which it exerts its effects will also be helpful

We used the contour-enhanced funnel plots to assess publication bias, if 10 or more trials were available for an outcome (Harbords test for dichotomous outcomes and Eggers test for continuous outcomes) [23, 24]