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Pfizer reported that while the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron was in line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury that resolved after discontinuation of danuglipron

For sensitive applications such as gene-expression profiling or receptor-binding work, the difference between 95% and 99% purity is operationally significant

A recent study tested this

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