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PK values, including trough values during dose escalation, were indicative of treatment compliance (ESM Fig

Ozempic significantly slows the rate at which food moves from the stomach into the small intestinea process that contributes to improved postprandial glucose control and enhanced satiety

By week 20, eGFR levels were similar between the semaglutide and placebo groups

In the current study, MTX induced a highly significant increase in the relative blood viscosity compared with the control rats, which may be attributed to the dehydration and hypernatremia that were observed after MTX treatment in our previous study 55