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Furthermore, the functional assessments of lower limbs of mice, including the reflexive mechanical pain-related responses experiment 34 and thermal pain-related responses experiment 35 , were conducted using the von Frey test and hot plate test, respectively

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LONP1 in human diseases As a central regulator of mitochondrial PQC, LONP1 dysregulation contributes to the pathogenesis of diverse human diseases, including neurological, cardiovascular, pulmonary, digestive, renal, reproductive, and musculoskeletal system disorders, and malignant tumors (Fig

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Identifying fungal biomarkers for non-invasive diagnosis and differentiating between diseases like MASLD and ALD also holds promise

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