Semaglutide serves as the active component in both Wegovy and Ozempic
(2021) investigated the primary tumor tissues collected from patients with T4Nx colorectal cancer, and they determined that CPT1A was downregulated in patients with peritoneal metastases
Hydrogen gas inhalation had no significant effect on the serum concentration of IL-5 (6.34 2.62 pg/ml), IL-13 (50.97 31.84 pg/ml), TNF- (30.17 6.16 pg/ml) and CXCL15 (11.82 4.24 pg/ml) in the asthmatic mouse model with or without hydrogen gas inhalation
The effect can be prolonged by lower gut bacterial action on fermentable fibers (see below) to produce short-chain fatty acids (propionate, butyrate, etc.) Healthful naturally-occurring animal fats such as tallow, lard, butter, and schmalz, the oils of fatty fish (salmon, mackerel, sardines, trout) and fruit and nut oils (coconut oil, olive oil, avocado oil, macadamia nut oil) activate free fatty acid receptors on Lcells to stimulate the release of GLP-1 from the gut and prolong its activity.There was early research that seemed to indict a diet high in saturated fats (what a surprise) as potentially toxic to the L-cells over time, but all that research was done in isolated cell models or high-fat/high carb rodent diets, not in a ketogenic diet context in humans
