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Nutrition, particularly adequate protein, micronutrients, and metabolic flexibility, ensures the brain is supplied with the substrates required to meet its exceptionally high energy demands [32]

Moreover, it makes the case that obesity (and its metabolic consequences) is the underpinning of HFpEF

A diversity score of 3 indicates an expected amount of diversity, with 4 & 5 indicating an increased distribution of bacteria based on the number of different species and their abundance in the sample, calculated based on Shannons diversity index

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