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Aftercare should follow the surgeons protocol because open, closed, revision, graft-based, and septorhinoplasty cases may need different restrictions

Unlike NSAIDs, acetaminophen works primarily in the brain and spinal cord rather than throughout the body, which explains why it's effective for pain and fever but doesn't reduce inflammation like NSAIDs do (Li et al., 2013

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Thus, we propose that these structural rearrangements are due to the positioning of the hydrogen bond, which could affect the flexibility of nearby loops, and possibly trigger the movement of the Cys190-containing loop ( Figure 7D )