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Mechanistically, upon activation, CRTC1 interacts with the CREB transcription factor and enhances the expression of CREB target genes like LYPD3 , a high-glycosylated cell surface protein, 513 ultimately augmenting cell migration and invasion, which contributes to esophageal cancer progression

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Previous studies have shown that GLP-1s can reduce pressure inside the skull, which is a possible cause of migraines, according to multiple health organizations