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Integrin beta 1 (ITG1), a critical cell surface protein, is actively expressed in the presence of GHK and thus may serve as a primary target for its anti-fibrotic effect [14]

This is achieved by expanding the internal diameter of the needle while maintaining the same external dimensions as a standard thin-walled needle, ensuring compliance with the ISO 9626:2026 requirements for the manufacture of hypodermic needles and medical devices

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