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Campbell DB, Li C, Sutcliffe JS, Persico AM, Levitt P

SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia

Furthermore, intraperitoneal injection of Alda-1 dramatically reduced rotenone and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal dopaminergic neuronal death, as well as ROS and 4-HNE levels, and reversed the decrease in mitochondrial membrane potential and expression of proteins related to the mitochondrial apoptotic pathway in mice 20

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