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It has been linked to regulating actin dynamics, wound healing, and angiogenesis, with studies suggesting potential anti-inflammatory activity via microRNA-146a

Abstract Background: Breast cancer continues to be the leading global health concern and cause of cancer-related deaths among women, with about 20 million new cases and 9.7 million deaths estimated globally based on GLOBOCAN 2022 data

Nevertheless, pollution, stress, exposure to the sun, unhealthy nutrition, and aging can cause skin to look dull, pigmented, and uneven

Interestingly, the previously unresolved region of DET1 spanning 7-11, which we named the claw, was found to bind to the backside of the Ube2e family members in the DDD-E2 complex (Supplementary Figs