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Diltiazem Co-administration of diltiazem hydrochloride extended-release with topiramate (150 mg/day) resulted in a 10% decrease in Cmax and a 25% decrease in diltiazem AUC, a 27% decrease in Cmax and an 18% decrease in des-acetyl diltiazem AUC, and no effect on N-desmethyl diltiazem

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To our knowledge, in addition to the whey protein effects [42], this is the only other report demonstrating that a targeted multi-nutritional supplement alone (independent of exercise) was also able to increase muscle mass among a population of older adults

Whether this is due to the limited increase in GLP-1 from 3.3 pM 0.5 pM (before LFD) to 3.6 pM 0.9 pM (after LFD) should be investigated in future studies