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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

By activating GLP-1 receptors, natural GLP-1 and GLP-1RAs reduce insulin resistance, suppress neuroinflammation and oxidative stress, and prevent negative changes in neuroplasticity

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Moreover, increasing focus on pediatric and elderly populations is vital, as T2DM prevalence rises in these groups