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324 Inhibition of the lncRNA MIR4435-2HG regulates macrophage M1/M2 polarization through the JAK1/STAT1 pathway, thus alleviating intestinal inflammation and colon injury

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It is a triple receptor agonist acting on GLP-1, GIP, and glucagon receptors, distinguishing it from currently approved dual or single agonists

Whilst Januvia modestly enhances the body's own incretin response, Mounjaro delivers a powerful, direct receptor activation that produces greater reductions in HbA1c and body weight, as demonstrated in clinical trials and documented in the EMA's European Public Assessment Report (EPAR)