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In light of the bidirectional relationship between NAFLD and sarcopenia and the significantly higher cardiovascular risk in obese sarcopenic patients compared to non-sarcopenic ones [143], GLP-1 RAs could guarantee additional direct benefits independent from weight loss and glycaemic control

But increasingly I am seeing patients who lost weight rapidly, on drugs or otherwise, and whose muscle quality tells a completely different story than their BMI does

If a provider determines that GLP-1 treatment is not appropriate for a given patient, no medication is prescribed

Q8: What is the ipamorelin dosing schedule for beginners