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A post hoc analysis of the phase IIb trial showed that tirzepatide was associated with a reduction in the level of high-sensitivity ICAM-1, CRP, and YKL-40 after 26 weeks of treatment in a dose-dependent manner [83, 103]

During weight loss, when eating patterns may fluctuate, topical vitamin C is especially helpful for maintaining a brighter, more even skin tone and brighter look

Patients taking tirzepatide should be counseled to seek immediate emergency medical attention for any symptoms suggestive of acute cardiac events