The most common side effects are injection-site soreness (41%, lasting 24-36 hours), mild nausea (12-15%, lasting 4-8 hours), and skin flushing (8-10%, lasting 10-30 minutes)
Additionally, decreased glycolysis has been observed in CD8+ T cells at rest and after activation (254), CD4+ T cells at rest (254), blood and urine samples (187), and PBMCs (388)
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The Future of MOTS-C Research: What Is Coming The MOTS-c field is advancing rapidly, with several threads of research likely to reshape clinical dosing recommendations within the next five years