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In addition, above the Na + -binding site (in the cavity, toward the extracellular side) we observe a second density that we have modelled as a water molecule (Fig

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The following adverse events, namely, vomiting, increased blood glucose, pancreatitis, abdominal pain, rash, blurred vision, gastrointestinal disorders, hospitalization, increased glycated hemoglobin, taste disturbances, respiratory difficulties, acute renal injury, peripheral edema, and diabetic ketoacidosis, are more commonly observed in oral administration

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