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Cadmium chloride induces non-alcoholic fatty liver disease in rats by stimulating miR-34a/SIRT1/FXR/p53 axis

[7] [8] The mechanism of action of tirzepatide involves stimulating insulin secretion in a glucose-dependent manner, meaning insulin release occurs primarily when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia

In animal studies, semaglutide use during pregnancy caused fetal death, structural abnormalities, growth alterations, and early pregnancy losses

A meta-analysis showed no statistically significant difference in efficacy between the two formulations at week 26, despite the numerically higher HbA1c response and body weight with sc semaglutide [59, 60]