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It contributes to the maintenance of healthy nervous system function and is crucial for DNA synthesis

The S2 classification reflects TB-500's structural connection to thymosin beta-4 and its documented growth factor activity

Beyond its cytoskeletal effects, TB-500 forms functional complexes with PINCH (particularly interesting new cysteine-histidine-rich protein) and integrin-linked kinase (ILK), activating the survival kinase Akt while inhibiting TNF--induced NF-B activation through blocking of RelA/p65 translocation