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MOS exert various pharmacological effects by modulating gut microbiota, enhancing immune function, and mitigating oxidative stress ( This study aimed to systematically investigate the mechanistic role of MOS in an experimental model of asthenozoospermia, with particular focus on its capacity to modulate sperm function via the microbiota-signaling axis. The findings are expected to provide theoretical and practical insights for the modern translational application of TCM-derived agents and for elucidating the role of gut microecology in male reproductive health
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