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reported one patient with 3-methylglutaric aciduria displayed thinning of the corpus callosum, enlarged lateral and third ventricles, and basal ganglia atrophy in cranial MRI

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Collectively, while ferroptosis plays a significant role in the pathogenesis of both TMJ OA and KOA, the specific effects may differ due to the distinct tissue characteristics, mechanical stress, and inflammatory environments of TMJ and knee