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Hazard ratios (HR) with 95% confidence intervals (CI) were calculated using univariable survival analyses

Thus, GLP-1-based therapy is nowadays widely used in the treatment of type 2 diabetes, especially in obese subjects

This evaluation should include assessment of body mass index (BMI) to confirm eligibility (BMI 30, or 27 with at least one weight-related comorbidity such as hypertension, dyslipidemia, type 2 diabetes, or obstructive sleep apnea), previous weight loss attempts, and realistic expectations for treatment outcomes