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(Frontiers in Pharmacology, 2022) reported pharmacokinetics and tissue distribution in rats and dogs, including a rapid plasma half-life under 30 minutes after IM or IV dosing
These beneficial effects were shown in the counteraction of glaucoma (i.e., normalization of increased intraocular pressure, maintained retinal integrity, recovered pupil function), the counteraction of retinal ischemia, and the control of pupil function [110,111,112,113]
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