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Gray urges people to consult with a healthcare professional for medical advice if the following occurs: You have not had a period in 3 months or longer You experience heavy bleeding lasting longer than 7 days You have had unpredictable periods for several months You experience severe pain, cramping, dizziness, or fatigue Your period does not regulate after a few months of taking your GLP-1/GIP medication The bottom line Zepbound and other weight loss medications may have an effect on your period

J Clin Endocrinol Metab, 2019

Nicotine Dependence: Just as in other substances, preclinical data is showing GLP-1RAs can reduce nicotine-seeking behaviors

November 12, 2025: Updated Sheds pricing for semaglutide and tirzepatide because they lowered their prices