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Although direct clinical evidence of systemic NAD(P) depletion during GLP-1RA therapy is lacking, experimental and observational studies suggest that NAD turnover and micronutrient status can be altered in obesity and inflammatory states [83, 85], supporting the biological plausibility of substrate-sensitive vulnerability

Some people lose more, some less, and your own results depend heavily on staying consistent with the medication, your eating plan, and movement

Both compounds target metabolic dysfunction but through distinct biological pathways, making them potential complement agents in a comprehensive weight loss strategy