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Signs and symptoms of hyperthyroidism and Graves disease Symptoms of hyperthyroidism may not develop until advanced stages of Graves disease, or may be overlooked or misdiagnosed

For example, in patients with renal insufficiency, high dose IVC may lead to kidney stone formation or acute oxalate nephropathy [65, 264], while a red cell glucose-6-phosphate dehydrogenase deficiency (G6PD) has been linked to cases of hemolytic anemia [66, 265] following high dose IVC, sugesting both of these condition should be screened for prior to high dose IVC administration

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