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Preclinical studies validate these direct anti-tumor effects across different agents: Liraglutide, for instance, demonstrates potent anti-cancer activity by suppressing HCC progression in mouse models, crucially exhibiting an anti-inflammatory effect by inhibiting the IL-6/STAT3 signaling pathway (Kojima et al., 2020

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11 Mechanism of Action As an important intracellular regulatory metabolite, GSH serves as both the prosthetic group of glyceraldehyde phosphate dehydrogenase and the coenzyme of glyoxalase and triose dehydrogenase

the SAG thus assimilated by the tissues is hydrolysed by cytoplasmic thioesterase and, by hydrolysis of the acetyl group, produces reduced GSH which is available for all the biological functions wherein it is required