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The once-weekly injection interval is designed to match this half-life, allowing new dose to layer onto remaining medication from the previous week, maintaining stable therapeutic levels

Do not discontinue tirzepatide without consulting your prescribing clinician , as abrupt cessation may affect your diabetes control or weight management goals

The results were striking: participants receiving the highest 12 mg dose achieved mean weight loss of approximately 24.2% of baseline body weight at week 48, compared to just 2.1% with placebo - representing an astounding 22 percentage point placebo-adjusted treatment effect

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