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Protect from direct light exposure and avoid repeated freeze-thaw cycles to maintain complex integrity and ensure consistent experimental results

Despite a relatively short half-life of approximately 30 minutes, the peptide triggers gene expression changes that persist and cascade independently of its continued presence

Riboflavin, in the form of FAD, acts as a cofactor of MTHFR and molecular studies show that the variant enzyme becomes inactive as a result of an increased propensity to dissociate from FAD (Reference Pejchal, Campbell and Guenther109,Reference Yamada, Chen and Rozen110)