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Note which side effects you experience and their severity

This proportional muscle loss is consistent with weight loss from any cause, including dietary restriction or bariatric surgery, but the rapidity of weight loss with these medications may make this effect more clinically apparent

If you are seeing a patient whose musculoskeletal presentation does not quite match a plausible mechanism of injury or evolves in unexpected ways, it is worth keeping an endocrine disorder on your clinical radar

A randomised trial found that patients who adhered to a low-calorie diet while on liraglutide lost significantly more weight than those who did not modify their diet, averaging an additional 3 kg over six months