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454,455 Unlike liver or tumor tissues, the dense extracellular matrix and dynamic contraction of the heart create significant physical barriers, limiting the distribution of RNA, protein, and cell therapies

Utzschneider et al., 2020), a major question remains: Do SCFAs produced in the gut reach the pancreas in relevant concentrations to influence local receptors

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In a recent study published in the International Journal of Obesity , researchers investigated the effects of combined glucagon-like peptide 1 (GLP-1) analog and bupropion/naltrexone treatment on weight loss