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These pockets exist thanks to a perfect storm of genetic predisposition, hormonal influences, and deeply structured fat that simply doesnt respond well to diet or exercise

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ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)

According to a study in Experimental Gerontology, The free radical theory of aging proposes that oxidative stress plays a key role in the aging process