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Some estimates suggest up to 25% of adults have some level of needle anxiety, which makes a daily drop or a patch sound like an easier alternative

It also includes the conclusions of studies carried out on experimental animals, explaining adequately that they cannot be extrapolated to humans until they are tested

The cardiovascular benefits are strongest when the depression actually improves, in people under 60, and in those with more severe depression

The most frequently reported adverse events were gastrointestinal in nature, including nausea (occurring in 25-33% of patients), diarrhea, vomiting, constipation, and abdominal discomfort