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These pathways were selected because they correspond to the core biological foundations of neurodegenerationproteinopathy, synaptic disfunction, neuroinflammation, mitochondrial impairment, vascular and metabolic dysregulation, among othersthereby anchoring the workflow in mechanisms that are central to dementias and making it applicable across AD, FTD, DLB, vascular and mixed dementias, as well as related neurodegenerative phenotypes that share these pathogenic mechanisms

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One of the reasons the rum tastes as it does, is because the master blender used to work for one of the awamori makers on Okinawa (it is a spirit akin to Shochu), and wanted to apply the methods of make to rum as well