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GLP-1s Show Promise in Treating Alcohol and Drug Addiction

Key findings at the highest dose (12mg weekly): Up to 24% mean body weight reduction over 48 weeks Significant reductions in fasting glucose and insulin resistance markers Meaningful reductions in liver fat content, relevant for participants with metabolic-associated fatty liver disease Once-weekly subcutaneous dosing was generally well-tolerated For context, semaglutide at its approved dose achieves approximately 1517% body weight reduction over 68 weeks

Appetite remains suppressed, but without the accompanying gastrointestinal distress that made eating difficult during month 2

Regardless of which type of GLP-1 you are using, the principles of titration remain the same