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Monitoring homocysteine levels and adopting a healthy lifestyle that includes a balanced diet and appropriate B vitamin supplements can help keep these levels within normal limits and reduce the risk associated with elevated homocysteine levels [12]

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Notably, treatment with Fer-1, a ferroptosis inhibitor, significantly alleviated pericyte injury ( postmortem striatal brain tissue from three patients with PD exhibited elevated FTH1 and IL-8 expression, closely recapitulating the transcriptional profile of microglia in the in vitro model