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Compound accumulation can induce lysosome membrane permeablization and cause cell death

Glucose/galactose adapted cells were cultured in DMEM containing 10% dFBS, 100 U ml 1 penicillin and 100 g ml 1 streptomycin, 1 mM sodium pyruvate and 25 mM glucose (Sigma-Aldrich, G7021-1KG) or 25 mM galactose (Sigma-Aldrich, G5388-500G) for a minimum of 1 month before being used experimentally

However, published research has demonstrated that the EPIC Study's minimum measurements of enlargement really are within the range of normal sized hearts for cavaliers

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