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These findings support the potential clinical utility of GPX4 inhibitors to prevent tumor relapse or to combat cancer cells that can adopt a therapy-resistant state

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Studies have also shown that GLP-1 can significantly increase the expression of GLP-1R through G protein-coupled receptor 119 (GPR119), enhance the activity of ABCA1, lead to the increase of apo AI, and thus promote intracellular cholesterol outflow [73]

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Ghosh et al., 2013

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Ascorbic acids antioxidant activity suppresses P-gp expression and is thought to have a positive effect on drug pharmacokinetics [39]

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