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Human GLP-2R protein colocalizes to 5-HT-containing cells in the epithelium, a neurotransmitter released by enteroendocrine cells (Guan et al., 2006)

Although length of treatment and experimental model differed per study, all observed a drop in ATP levels and a depletion of NAD following exposure to high-dose VitC, in line with the inhibition of energy metabolism and multifaceted metabolic rewiring described in numerous pre-clinical studies using alternative approaches

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