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Description

From both a structural and functional perspective, OCTN2 is a marked departure from other members of the SLC22 family, and presents the transport mechanism of the OCTN sub-family (Fig

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The broader picture has proven to be a little more complex than initially thought

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"Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application"

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Accumulated ROS cause oxidative damage to lipids, DNA, and proteins, creating a pro-degenerative cellular environment (Chang and Chen, 2020

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