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For patients who cannot tolerate the target dose, stepping back one dose tier and holding for four to eight additional weeks is preferred over immediate discontinuation

Polyalkylimide Benefits: This filler is compatible with human tissue and, thus, reduces the risk of allergic reactions and adverse effects

Though the majority of cannabis users do not proceed to develop a CUD, approximately 10% do, and among young users, the risk can increase to 30% [46]

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