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Current Obesity Reports, 8 (2), 156164

According to Lillys release, the trial met its primary endpoint: participants titrating up to the highest orforglipron dose lost 27.3 lb (12.4%) of body weight at 72 weeks versus about 0.9% weight loss with placebo

Participants had normal vital signs, 12-lead electrocardiogram results and clinical laboratory tests at the time of randomization