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By targeting multiple pathways simultaneously, these next-generation drugs may further enhance brain health, improve vascular integrity and potentially provide stronger protection against conditions like cognitive impairment, vascular dementia and ADRD, she wrote

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Informed by the structural data of Pt GSTF8, the accompanying mutagenesis experiments and the QM/MM studies, we investigated the impact of a disulfide bond between C13 and GSH on dehydratase activity

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