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All analyses were performed using linear mixed models with family-factor as random effect, in order to take into account the pedigree structure of the sample

[5] The metabolite S-adenosyl methionine (SAM) of methionine, which has lipotropic properties, may be responsible

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Furthermore, environmental pollutants, determining the formation of DNA adducts and abasic sites construction, can induce DNA modifications in gametes and embryos by introducing genetic mutations once unrepaired ( Nutritional Disorders A normal reproductive performance definitely requires a healthy nutrition since malnourished males and females are reported as major infertile populations in developing countries while, eating in excess, fast food consumption, hypercaloric dietary regimens and obesity, concur to infertility in well-developed and western societies