what are the side effects for glp-1 Overdose risks increase as demand injectable weight-loss drugs on rise, research finds long term glp 1 side

Glycaemic and non-glycaemic efficacy of once-weekly GLP-1 receptor agonists in people with type 2 diabetes

This means these medications may need to be used long-term to maintain benefits

DAMPs also impact Kupffer cells, activating the nucleotide-binding oligomerization domain-like receptor (NLR) Family, Pyrin Domain-Containing 3 protein (NLRP3), a type of inflammasome leading to IL-1 secretion and inflammation, and pyroptosis, releasing more DAMPs and perpetuating a destructive cycle (Hammerich and Tacke, 2023)

The median HbA1C level of all T2D subjects treated at VUMC was maintained at approximately 7.0 in the past 17 years, suggesting that overall, diabetes is well-controlled in this cohort