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The tumor suppressor protein p53 increases the expression of the aspartate/glutamate transporter SLC1A3 and the arginine transporter SLC7A3 upon glutamine depletion, leading to resistance to treatments that deplete extracellular glutamine 114,115
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Specifically, this peptide seemed to suppress the growth of two types of cancer cells in experimental settings: SH-SY5Y neuroblastoma cells, which are a model for studying nerve cell behavior and pathology, and U937 histiocytic lymphoma cells, which are used to study the immune system's response to cancer
It does not provide immediate wrinkle reduction but may improve skin quality over time by supporting repair processes
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