Palomba S, Santagni S, La Sala GB
This publication has not independently verified body-composition outcomes from the protocol - patients should discuss protein intake, resistance training, and lean-mass preservation with their licensed provider
A recent retrospective study involving a large sample size of 1,890,020 diabetic patients found that GLP-1RAs were associated with a significantly lower risk of hepatocellular carcinoma compared to insulin and other diabetic medications over a 5-year follow-up period ( Pre-clinical studies investigating the impact of GLP-1 RAs specifically on breast cancer progression have produced conflicting results, which vary based on the receptor status of the cancer cell lines studied ( in vitro ( in vitro study by Zhao et al., liraglutide reduced cell proliferation and increased cell apoptosis in estrogen receptor-positive breast cancer cells ( in vitro studies by Alanteet et al
Under the terms of the alliance, Ascendis will carry out the early development of TransCon product candidates, funded by Novo Nordisk, with the pharma group taking over once they reach the clinical development stage.
